Free-running circadian rhythm disorder in the sighted – case report & discussion

Transient short free running circadian rhythm in a case of aneurysm near the suprachiasmatic nuclei.

A free running circadian rest-activity cycle is rare in sighted individuals living in a normal environment. Even more rare is a periodicity shorter than 24 hours, as observed in actigraphic recordings in a female patient during convalescence after a whiplash injury in a car accident. The documented free running period was 22.5 hours for 19 days. During the subsequent weeks re-entrainment occurr...

Circadian Rhythm and Bipolar Disorder Impact of Circadian Rhythm Disturbances in Bipolar Disorder

Circadian Rhythm Sleep Disorders: Part II, Advanced Sleep Phase Disorder, Delayed Sleep Phase Disorder, Free-Running Disorder, and Irregular Sleep-Wake Rhythm

(Section numbers run consecutively through Parts I and II) 9.0 Introduction 10.0 CRSDs and Molecular Genetics 11.0 Advanced Sleep Phase Disorder (ASPD) 11.1 Diagnostic Issues 11.2 Risk Factors 11.2.1 Age 11.2.2 Gender 11.2.3 Light Exposure 11.3 Assessment Tools 11.3.1 Sleep Logs and Actigraphy 11.3.2 Morningness-Eveningness Questionnaire (MEQ) 11.3.3 Polysomnography (PSG) 11.3.4 Phase Markers 1...

Circadian Rhythm Sleep Disorder: Irregular Sleep Wake Rhythm Type.

Irregular Sleep Wake Rhythm Disorder (ISWRD) is characterized by the relative absence of a circadian pattern in an individual's sleep-wake cycle. Significant changes in circadian regulation occur with aging and with neurodegenerative diseases, such as Alzheimer's disease prevalent in older adults, which are likely to contribute to the prevalence of ISWRD seen in these populations, although ISWR...

Larval ethanol exposure alters adult circadian free-running locomotor activity rhythm in Drosophila melanogaster.

Alcohol consumption causes disruptions in a variety of daily rhythms, including the sleep-wake cycle. Few studies have explored the effect of alcohol exposure only during developmental stages preceding maturation of the adult circadian clock, and none have examined the effects of alcohol on clock function in Drosophila. This study investigates developmental and behavioral correlates between lar...